Products >> Fungicides >> Flutriafol

Flutriafol

Flutriafol 95%TC
Flutriafol 25% SC

Fungicide
FRAC 3; DMI: triazole

NOMENCLATURE
Common name flutriafol (BSI, ANSI, draft E-ISO, (m) draft F-ISO)
IUPAC name (RS)-2,4'-difluoro-a-(1H-1,2,4-triazol-1-ylmethyl)benzhydryl alcohol
Chemical Abstracts name (?-a-(2-fluorophenyl)-a-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol

Flutriafol APPLICATIONS
Biochemistry Inhibits ergosterol biosynthesis (steroid demethylation inhibitor), causing fungal cell wall collapse and inhibition of hyphal growth. Mode of action Contact and systemic fungicide with eradicant and protective action. Absorbed by the foliage, with translocation acropetally in the xylem. Uses Control of a broad spectrum of leaf and ear diseases (including Erysiphe graminis, Rhynchosporium secalis, and Septoria, Puccinia, and Helminthosporium spp.) in cereals, at 125 g a.i./ha. Also used in non-mercurial seed treatment formulations to control the major soil-borne and seed -borne diseases of cereals. Formulation types SC. Selected tradenames: 'Impact' (Cheminova); mixtures: 'Vincit' (+ imazalil+ thiabendazole) (Cheminova)

OTHER TRADENAMES
'Cicero' (Cheminova); 'Pointer' (Cheminova) mixtures: 'Early Impact' (+ carbendazim) (Cheminova); 'Ferrax' (+ ethirimol+ thiabendazole) (seed) (Syngenta, Cheminova); 'Halo' (+ chlorothalonil) (Syngenta, Cheminova); 'Impact Excel' (+ chlorothalonil) (Syngenta, Cheminova); 'Pacer' (+ carbendazim) (Cheminova); 'Palette' (+ carbendazim) (Cheminova); 'PP 375' (+ chlorothalonil) (Syngenta, Cheminova); 'Prospa' (+ chlorothalonil) (Syngenta, Cheminova)

ANALYSIS
Residues by glc; details from Syngenta.

MAMMALIAN TOXICOLOGY
Oral Acute oral LD50 for male rats 1140, female rats 1480 mg/kg. Skin and eye Acute percutaneous LD50 for rats >1000, rabbits >2000 mg/kg. Mild eye irritant; non-irritating to skin (rabbits). Not a skin sensitiser. Inhalation LC50 (4 h) for rats >3.5 mg/l. NOEL In 90 d feeding trials, rats receiving 2 mg/kg diet, and dogs receiving 5 mg/kg daily showed no ill-effects. Non-teratogenic in rats and rabbits. Other Non-cytogenic in in vivo studies. Non-mutagenic in the Ames assay. Toxicity class WHO (a.i.) III; EPA (formulation) III EC hazard (Xn; R20/21/22| R52, R53)

Flutriafol ECOTOXICOLOGY
Birds Acute oral LD50 for female mallard ducks >5000 mg/kg. Dietary LC50 (5 d) for mallard ducks 3940, Japanese quail 6350 mg/kg. Fish LC50 (96 h) for rainbow trout 61, mirror carp 77 mg/l. NOEC 6.2 mg/l. Daphnia LC50 (48 h) 78 mg/l. Bees Low toxicity to honeybees. Acute oral LD50 >5 mg/bee. Worms LC50 (14 d) >1000 mg/kg.

Flutriafol ENVIRONMENTAL FATE
Soil/Environment Flutriafol has no effect on microbial populations, or on the carbon or nitrogen transformations occurring in the soil.